Dr Dayan Goodenowe Discusses Plasmalogen Deficiency, Dementia, and Death.

Plasmalogens are a subset of phospholipids. They concentrate on the brain and the heart. Plasmalogens is not just traced nutrients; they make up a significant portion of the brain, accounting for up to 20% of its dry weight.

Plasmalogens serve as a storage site for essential fatty acids such as oleic acid, arachidonic acid, and docosahexaenoic acid (DHA). Plasmalogens are anti-inflammatory, powerful antioxidants, a critical component of cell membranes, lipoproteins, myelin, and synaptic membranes, and a major structural component of lipoproteins, myelin, and synaptic membranes.

Plasmalogen levels in the brain rise until the age of 30 to 40, then fall precipitously by 70. There are insufficient food supplies. Plasmalogens are produced by the body in cell peroxisomes, with the liver producing the vast majority. The body's ability to produce plasmalogens hamper when peroxisome function deteriorates with age, and plasmalogens are destroyed due to inflammation and oxidative stress.

Why are low plasmalogen levels harmful?

There is no doubt that plasmalogens are beneficial to health. But what about low plasmalogen levels - how terrible can they be? I've created a lot of graphs in my profession, but only one has ever worried me: the association between blood plasmalogen levels and death. 

Plasmalogen levels in the brain rise until the age of 30 to 40, then fall precipitously by 70. There are insufficient food supplies. Plasmalogens are produced by the body in cell peroxisomes, with the liver producing the vast majority. The body's ability to produce plasmalogens is hampered when peroxisome function deteriorates with age, and plasmalogens are destroyed due to inflammation and oxidative stress.

Why are low plasmalogen levels harmful?

There is no doubt that plasmalogens supplements are beneficial to health. But what about low plasmalogen levels - how terrible can they be? I've created a lot of graphs in my profession, but only one has ever worried me: the association between blood plasmalogen levels and death. Why are plasmalogen levels so low?

The body generates and uses a large number of plasmalogens. When the body can no longer produce as much plasmalogen as it consumes, the condition is known as plasmalogen deficit. It can occur due to increased oxidative stress, which destroys plasmalogens8, or as a result of reduced production caused by ageing and prolonged xenobiotic exposure.

The next steps.

We accept pre-orders for Prodrome-Neuro Plasmalogen Oil until we fulfil the regulatory prerequisites to make Prodrome-Neuro available for personal use; it is presently only available for research purposes. Several studies are now underway to support dose and establish tissue levels and safety.

Enrollment in a clinical trial funded by the Alzheimer's Association to use Prodrome-Neuro Plasmalogen Oil in Alzheimer's patients begins in 2020. Our goal is to broaden the clinical trial to include people with Parkinson's disease and multiple sclerosis.

It's obvious.

While research on plasmalogens continues to improve in order to address crucial concerns about their role in illness management, one thing is evident today: plasmalogens are a vital brain nutrient that you do not want to be deficient in. Our natural plasmalogen supplement is scientifically formulated to ensure an adequate amount of plasmalogens in the blood supply for wellness.

Dr Goodenowe's research on plasmalogens continues to advance to answer critical challenges involving their use in sickness management. One thing is certain today: plasmalogens are a critical brain vitamin that you should not be deficient in. Our natural plasmalogen supplement has been carefully designed to ensure an adequate number of plasmalogens in the blood supply for wellbeing.